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Storage conditions can influence the rate of recovery loss. ### Key Sections of Technical Report 82
Techniques to "unmask" endotoxins so they become detectable again (e.g., using magnesium, albumin, or specific dispersants).
LER occurs when a known amount of endotoxin is added to a drug product but cannot be recovered or detected during testing over time. This is not a failure of the test itself, but rather a where the endotoxin molecules (LPS) are rearranged into structures that the Limulus Amebocyte Lysate (LAL) reagent cannot recognize. Common LER Triggers
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